Arena Pharmaceuticals' Presence at United European Gastroenterology Week Bolsters Commitment to the Gastrointestinal Disease Community
In addition to the data presentations, Arena is sponsoring a satellite breakfast symposium (details below) and exhibiting at booth #78. Find out more about Arena's ongoing and planned clinical trials in inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS).
Arena Sponsored Breakfast Symposium Details:
Title: Will oral therapies change the IBD treatment landscape?
Location: Fira Gran Via, Hall 8 –
How: Learn more and register here
Etrasimod Presentation Details:
Title: Long-term Efficacy and Safety of Etrasimod for Ulcerative Colitis: Results from the Open- label Extension of the Oasis Study
Presentation Time: 12:30 –
Presenting Author: Dr. Séverine Vermeire
Location: Poster Hall 7
Poster Identification: #P0403
Olorinab Presentation Details:
Title: Preclinical and Clinical Efficacy of Olorinab, a Peripherally Restricted, Highly Selective Full Agonist of the Cannabinoid Receptor 2 for the Management of Visceral Pain in Inflammatory Bowel Disease
Presenting Author: Dr. Peter Higgins
Abstract Identification: #OP212
Etrasimod (APD334) is a once-daily, oral, selective sphingosine 1-phosphate (S1P) receptor modulator, discovered by Arena, designed to provide systemic and local cell modulation by targeting S1P receptor subtypes 1, 4 and 5. Etrasimod has therapeutic potential in immune and inflammatory-mediated diseases such as ulcerative colitis, Crohn's disease, and atopic dermatitis. S1P receptors have been demonstrated to be involved in the modulation of several biological responses, including lymphocyte trafficking from lymph nodes to the peripheral blood. By isolating subpopulations of lymphocytes in lymph nodes, fewer immune cells are available in the circulating blood to effect tissue damage.
Olorinab (APD371) is an oral, peripherally acting, highly selective, full agonist of cannabinoid receptor 2 (CB2) in development for the treatment of visceral pain associated with gastrointestinal (GI) diseases, including Crohn's disease and irritable bowel syndrome (IBS). Evidence that CB2 are expressed in multiple cell types of the GI tract, and modulate intestinal inflammation and visceral hypersensitivity, make CB2 an attractive target for the treatment of abdominal pain in GI disorders.
Etrasimod and olorinab are investigational compounds that are not approved for any use in any country.
Arena has additional license agreements and partnerships, including with
Certain statements in this press release are forward-looking statements that involve a number of risks and uncertainties. These forward-looking statements may be identified by introductory words such as "will," "planned," "designed to," "potential," "in development for," "driven to," "potentially," "evaluating," or words of similar meaning, or by the fact that they do not relate strictly to historical or current facts. Such forward-looking statements include, without limitation, statements about Arena's participation in UEG Week, including its breakfast symposium, data presentations, and booth; the opportunity, development and potential of etrasimod and olorinab; Arena's drive; and the potential of Arena's assets, programs, licenses, and partnerships. For such statements, Arena claims the protection of the Private Securities Litigation Reform Act of 1995. Actual events or results may differ materially from Arena's expectations. Factors that could cause actual results to differ materially from the forward-looking statements include those disclosed in Arena's filings with the
Executive Vice President and
Chief Financial Officer
Matt Middleman, MD
LifeSci Public Relations
View original content to download multimedia:http://www.prnewswire.com/news-releases/arena-pharmaceuticals-presence-at-united-european-gastroenterology-week-bolsters-commitment-to-the-gastrointestinal-disease-community-300941014.html