Arena Pharmaceuticals, Inc.
Oct 17, 2007

Arena Pharmaceuticals Announces Third Quarter 2007 Financial Results

SAN DIEGO, Oct. 17 /PRNewswire-FirstCall/ -- Arena Pharmaceuticals, Inc. (Nasdaq: ARNA) today reported financial results for the third quarter ended September 30, 2007.

Total revenues in the third quarter of 2007 were $5.0 million, compared to $4.4 million in the third quarter of 2006. Total revenues in the first nine months of 2007 were $14.8 million, compared to $25.9 million in the first nine months of 2006. Revenues in the first nine months of 2006 included $9.0 million from milestones received under Arena's collaborations with Ortho-McNeil Pharmaceutical, Inc. and Merck & Co., Inc. Arena reported a net loss allocable to common stockholders in the third quarter of 2007 of $32.8 million, or $0.54 per share, and a net loss allocable to common stockholders in the first nine months of 2007 of $104.4 million, or $1.71 per share. This compares with a net loss allocable to common stockholders in the third quarter of 2006 of $20.1 million, or $0.43 per share, and a net loss allocable to common stockholders in the first nine months of 2006 of $51.9 million, or $1.14 per share.

"This past quarter we achieved significant company milestones in both our lorcaserin obesity program and our APD125 insomnia program. We announced a positive month 6 independent ESMB review in our lorcaserin Phase 3 BLOOM trial and positive APD125 Phase 2 results," stated Jack Lief, Arena's President and Chief Executive Officer. "We continue to achieve the milestones we have guided to over the last few years. Through sustained focus and innovation, we continue to prove our ability to discover and develop novel therapeutics."

Research and development expenses totaled $32.2 million in the third quarter of 2007, compared to $22.7 million in the third quarter of 2006. Research and development expenses in the first nine months of 2007 totaled $108.8 million, compared to $65.3 million in the first nine months of 2006. The increase in research and development expenses is primarily attributable to increased clinical trial costs related to the Phase 3 lorcaserin BLOOM (Behavioral modification and Lorcaserin for Overweight and Obesity Management) trial and the Phase 2 APD125 trial for the treatment of insomnia. Research and development expenses in the first nine months of 2007 included $3.1 million in non-cash, stock-based compensation expense, compared to $2.2 million in the first nine months of 2006. General and administrative expenses totaled $7.9 million in the third quarter of 2007, compared to $3.9 million in the third quarter of 2006. General and administrative expenses in the first nine months of 2007 totaled $19.6 million, compared to $13.2 million in the first nine months of 2006. This increase in general and administrative expenses is primarily attributable to non-cash, stock-based compensation expense and patent costs, some of which are reimbursed by Arena's collaborators. General and administrative expenses in the first nine months of 2007 included $3.9 million in stock-based compensation, compared to $1.6 million in the first nine months of 2006.

Cash, cash equivalents and short-term investments totaled $339.1 million at September 30, 2007. Approximately 61.2 million shares of common stock were outstanding at September 30, 2007.

Arena's Third Quarter Highlights

Scheduled Earnings Call

Arena will host both a conference call and a webcast to discuss the third quarter 2007 financial results, and to provide a corporate update today, Wednesday, October 17, 2007, at 5:00 p.m. Eastern Time (2:00 p.m. Pacific Time). Jack Lief, President and Chief Executive Officer and Robert E. Hoffman, Vice President, Finance and Chief Financial Officer will host the conference call.

The conference call may be accessed by dialing 866.713.8563 for domestic callers and 617.597.5311 for international callers. Please specify to the operator that you would like to join the "Arena Third Quarter Earnings Call." The participant code for the call is 65424387. The conference call will be webcast live under the investor relations section of Arena's website at http://www.arenapharm.com, and will be archived there for 30 days following the call. Please connect to Arena's website several minutes prior to the start of the broadcast to ensure adequate time for any software download that may be necessary.

Upcoming Corporate Presentations

Arena is currently scheduled to present at the following investment and industry conferences through November 2007:

About Arena Pharmaceuticals

Arena is a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing oral drugs in four major therapeutic areas: cardiovascular, central nervous system, inflammatory and metabolic diseases. Arena's most advanced product candidate, lorcaserin, is being investigated in a Phase 3 clinical trial program for the treatment of obesity. Arena's broad pipeline of novel compounds targeting G protein-coupled receptors, an important class of validated drug targets, includes compounds being evaluated independently and with its partners, Merck & Co., Inc. and Ortho-McNeil Pharmaceutical, Inc.

Arena Pharmaceuticals® and Arena® are registered service marks of the company. "APD" is an abbreviation for Arena Pharmaceuticals Development.

Forward-Looking Statements



Certain statements in this press release are forward-looking statements that involve a number of risks and uncertainties. Such forward-looking statements include statements about the significance of Arena's recent milestones in its lorcaserin and APD125 programs and data therefrom, Arena's ability to discover and develop novel therapeutics, the tolerability, side effects, efficacy and potential of Arena's product candidates and compounds, the protocol, design, scope and other aspects of the Phase 1 clinical trial of APD791, and about Arena's strategy, internal and partnered preclinical and clinical programs, and ability to develop compounds and commercialize drugs. For such statements, Arena claims the protection of the Private Securities Litigation Reform Act of 1995. Actual events or results may differ materially from Arena's expectations. Factors that could cause actual results to differ materially from the forward-looking statements include, but are not limited to, Arena's planned clinical trials may not proceed at the time Arena expects or at all, the results of preclinical studies or clinical trials may not be predictive of future results, Arena's ability to partner lorcaserin, APD125, APD791 or other of its compounds or programs, the timing, success and cost of Arena's research, out-licensing endeavors and clinical trials, Arena's ability to obtain additional financing, Arena's ability to obtain and defend its patents, and the timing and receipt of payments and fees, if any, from Arena's collaborators. Additional factors that could cause actual results to differ materially from those stated or implied by Arena's forward-looking statements are disclosed in Arena's filings with the Securities and Exchange Commission. These forward-looking statements represent Arena's judgment as of the time of this release. Arena disclaims any intent or obligation to update these forward-looking statements, other than as may be required under applicable law.


                           Arena Pharmaceuticals, Inc.
                 Condensed Consolidated Statements of Operations
                    (In thousands, except per share amounts)

                                   Three months ended     Nine months ended
                                       September 30,         September 30,
                                     2007       2006       2007        2006
                                       (unaudited)            (unaudited)
    Revenues
      Total revenues              $  5,041   $  4,416   $  14,763   $ 25,870

    Expenses
    Research and development        32,219     22,727     108,834     65,293
    General and administrative       7,885      3,900      19,648     13,238
    Amortization of acquired
     technology                        385        385       1,153      1,153
      Total expenses                40,489     27,012     129,635     79,684

    Interest and other income,
     net                             3,170      2,972      12,092      3,455
    Net loss                       (32,278)   (19,624)   (102,780)   (50,359)
    Dividends on redeemable
     convertible preferred stock      (535)      (514)     (1,574)    (1,511)
    Net loss allocable to common
     stockholders                 $(32,813)  $(20,138)  $(104,354)  $(51,870)

    Net loss per share allocable
     to common stockholders,
     basic and diluted            $  (0.54)  $  (0.43)  $   (1.71)  $  (1.14)

    Shares used in calculating
     net loss per share allocable
     to common stockholders,
     basic and diluted              61,007     47,242      60,887     45,620



                           Arena Pharmaceuticals, Inc.
                    Condensed Consolidated Balance Sheet Data
                                 (In thousands)

                                                September 30,    December 31,
                                                    2007             2006
                                                 (unaudited)        (Note)

    Assets
      Cash, cash equivalents and short-term
       investments                                $339,118         $388,825
      Accounts receivable                              793              310
      Other current assets                          12,695           10,551
      Land, property and equipment, net             58,523           56,500
      Acquired technology,
       investments and other assets                 14,196           12,279
           Total assets                           $425,325         $468,465

    Liabilities and Stockholders' Equity
      Deferred revenues                           $  6,142         $ 13,054
      Other current liabilities                     31,246           22,947
      Lease financing obligations &  other
       long-term liabilities                        62,927           14,541
      Redeemable convertible preferred stock        53,382           51,808
      Stockholders' equity                         271,628          366,115
           Total liabilities and
            stockholders' equity                  $425,325         $468,465

    Note: The Condensed Consolidated Balance Sheet Data has been derived from
          the audited financial statements as of that date.

    

SOURCE Arena Pharmaceuticals, Inc.

CONTACT: Jack Lief, President and CEO, or David Walsey, Director, Corporate Communications, both of Arena Pharmaceuticals, Inc., +1-858-453-7200 ext. 1682; or Mary Claire Duch, Media Relations of WeissComm Partners, +1-212-301-7228, for Arena Pharmaceuticals, Inc.
Web site: http://www.arenapharm.com